NAE list of engineering challenges…which ones are the top?

Which engineering challenges do you see as the top or most important in the years ahead?

http://www8.nationalacademies.org/onpinews/newsitem.aspx?RecordID=02152008

Affordable solar energy….thin cell technology?
Reverse-engineering the human brain?
Converting waste products into energy via plasma-gasification?
Any others you would add to the list?

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